Zymetrix has expertise in characterizing the phenotypic state of cellular biomaterials, particularly in terms of their response to mechanical loads. The core techniques that Zymetrix has available include the following:
- Protein, DNA and RNA extraction and purification
- Gel electrophoresis (SDS-PAGE), Western and functional expression analysis of conditioned media
- Qualitative and quantitative gene expression profiling using PCR and RT-qPCR. This includes an Applied Biosystems Viia7 real-time PCR with TaqMan® Array Card block for medium to high throughput.
- Measurement of gene expression, protein expression and drug penetration via imaging (confocal, microCT, MRI)